This should work with Domoticz, it's what I intend to use with it. I've received the boards from China and I'm currently working on a version 2 of this board. There are some errors in the design of version 1 that I need to get out. New version will be up shortly.
@WiktorDIY The ch340 are notorious for being broken. The best I ever achieved was 19200 and flakey..
I purchased a real Nano not a ch knock off eg uses a different uart no problems
