Coronavirus (way, way, off topic)


  • Hero Member

    I'm curious how it's going with you all in whatever country you're in. Nothing better than first hand reports.

    Here, the US is effectively shut down for now. I predict the military will be deployed to set up emergency field hospitals to handle the expected surge that will undoubtedly overwhelm existing hospitals. If they do it now, there may just be enough time to pull it off and train soldiers to intubate people. Fingers crossed. NY has already asked for federal help, so it's either that or the national guard. What else is there? FEMA couldn't handle even a hurricane, and the scale of this is, I'm guessing, 1000x bigger than that.

    Canada has closed their US boarder to keep US health refugees from flooding into their country. I can't blame them.

    Unfortunately, the true limiter may be the number of ventilators. Time for an epic open source project?

    Perhaps people can 3D print their own intubation stents though. Not a perfect solution, but perhaps better than nothing? Might have to use chemical sterilizers to avoid melting it. I haven't seen any yet on thingiverse, but something to think about for those who have the skillz....

    As for me, I wouldn't be surprised if I've already had it. My family and I have been pinned down for the last couple of weeks with some kind of flu/who--knows-what. My wife thinks we got hit by something else, but if it isn't coronavirus, it's a flu that's damn similar and quite a coincidence. No way to know, though, as test kits aren't easily available.


  • Hardware Contributor

    @NeverDie
    I guess here (FR), it's quite like in others countries.. very sad.
    Shutdown for two weeks at least, borders closed for 30d. Going out without a paper=penalty (130€).
    Military deployed to help overwhelmed hospitals (especially in East which is epicenter here), "hopefully" I live in West. Hospitals missing protection, intubators etc..
    We're a "small" country, with good healthcare, hopefully for sick people. Still It doesn't touch only old persons, there are reports of 25-40years old people deaths too.
    Today, deaths have doubled here.

    Personnaly, I started to limit my visits when it started in China, because I never trust when someone tells me the big cloud stopped at the borders, and didn't want to get caught and transmit to people I love..
    I think govs should all have taken decisions when it started instead of waiting "will I get the flu or not??" And here we are now .. 😬

    Well, it's very sad. Praying for sick people, doctors, nurses who are on the frontline. I hope a lab will find the remedy soon.

    And I hope it'll be fine for you and your family too.



  • @NeverDie Worth a read as a lot of info not explained by the political crew or the media... The infectivity and when it peaks is the most illuminating, it explains why it spread so dramatically, and why isolation, distancing, sitting tight and testing were so effective...
    As an aside to the lunacy, Chinese sent a planeload of gear and advisers to help in Italy with their experience in dealing with COVID.
    No use to Trumpland of course, the CHINESE VIRUS is unknown outside the US 😉
    https://www.sciencenews.org/article/coronavirus-most-contagious-before-during-first-week-symptoms



  • RO instigated guidance on distancing, touching etc., no more than 50 in a group, as of last Monday, not a huge problem but for old habits like shaking hands, it looks like a game of rock, scissors paper on occasion.
    The authorities are watching like hawks and will respond rapidly to any emerging pattern, much as all european countries now are after Lombardy went from OH to SHIT in days.
    The greatest risks are in cities obviously because of proximity, but with Chinese and Korean on experience on mass disinfection gives them all they need to know what to do.
    Glad I'm out in a nice village with plenty of space around, no guarantee that will last of course but no report of anything close.

    The medics are those in greatest danger in all this, thereby compounding the problem when they are not protected, screened, tested. The UK could be next to go into meltdown with catastrophic leadership and response for the above reasons, will leave those there to example why it is the perfect storm...


  • Hero Member

    @zboblamont said in Coronavirus (way, way, off topic):

    CHINESE VIRUS

    I think he's calling it that as a reaction to and to sandbag against Chinese allegations that it was started by the US.

    It turns out there is a basis for those Chinese suspicions. USAID actually created a man-made chemeric coronavirus in their lab and reported the results in November 9, 2015 Nature.
    https://www.nature.com/articles/nm.3985 If that article doesn't make the hair on the back of your neck stand on end, I don't know what will. Here's an excerpt:

    Here we examine the disease potential of a SARS-like virus, SHC014-CoV, which is currently circulating in Chinese horseshoe bat populations1. Using the SARS-CoV reverse genetics system2, we generated and characterized a chimeric virus expressing the spike of bat coronavirus SHC014 in a mouse-adapted SARS-CoV backbone. The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin converting enzyme II (ACE2), replicate efficiently in primary human airway cells and achieve in vitro titers equivalent to epidemic strains of SARS-CoV.

    And, there were alarms raised at the time:
    https://www.the-scientist.com/news-opinion/lab-made-coronavirus-triggers-debate-34502
    And the CEO of USAID just recently resigned for no good reason. So, while proving nothing, maybe that is grounds for suspicion. Or, maybe the Chinese themselves were conducting similarly foolish experiments and something got into the wild (https://www.the-scientist.com/news-opinion/theory-that-coronavirus-escaped-from-a-lab-lacks-evidence-67229). After all, the Chinese have a history of letting SARS viruses escape from their labs (https://www.the-scientist.com/news-analysis/sars-escaped-beijing-lab-twice-50137), so it's not unimaginable. That said, it's worth noting that scientists in the field don't even consider a man-made virus as one of the possible origens:
    https://www.nature.com/articles/s41591-020-0820-9
    perhaps because there's no need to reach for that. It shall be interesting if Patient Zero can be identified and whether he/she was a bat eating weirdo, which is the popular theory, or whether this is the Chernobyl of bio-research.

    Personally, my bet is on the animal source. When I visited China in the 1980's, any and every animal that could be caught by humans was caught, flattened, dried out, and sold in the markets. And by that I mean rats, lizards, snakes, you name it. Fairly disgusting, but maybe not if you were raised eating that and your alternative is death by starvation. So, for those reasons, I suspect poverty may be the root of it all, just as it was with bush meat in Africa leading to Ebola. It's hard to heap blame on people of limited means who are trying to survive and just barely hanging on. For that reason, I see it as a societal failure, and I hope covid-19 will motivate them to fix it (and not just make empty promises that they'll fix it, as was the case with previous SARS). Sigh, it probably won't happen though unless covid-19 turns out to be so terrible that the whole world unites and truly demands it. And so, to avoid that, I think that's why the Chinese are busy trying to blame it on to the US, which, let's face it, did immoral research on its own population in the past (e.g. in 1950 the US military dosed the San Francisco population with bacteria just to see how it would spread: https://en.wikipedia.org/wiki/Operation_Sea-Spray).

    Regardless, I think investigators should dig as deep as they need to in order to be certain as to the true cause of it all. Let's get all the facts and leave no stone un-turned. The name calling is just a distraction from that.


  • Hardware Contributor

    Here in Vietnam as a China neighbour they took things very seriously from the start. There is a very strict quarantine rule, where everyone in contact with sick people is quarantined or home-quarantined, and then all their contacts, and so on up to sometimes 4-5 levels.
    It helps but there are still people who are in the incubation period in the country, and this morning they announced there was one case in my building, a guy who came from UK 10 days ago. So they have quarantined the building and we can't go out for 2 weeks. The same will probably happen to all visitors (they know have to sign a register so it's easy to trace them), the people we have been in contact with, etc etc

    I was sceptical at first when seeing the extreme precautions they used as we had 3 weeks without any new case in the country but they still didn't want to reopen the schools (closed since early February, right after Têt = Vietnamese new year). But now we can see things in Europe, US etc, while here we have less than 80 cases for 100 millions pple, and less than 10 cases per day, most of them being fresh arrivals to the country, I realize they were one of the very few countries in the world to take enough precautions.

    They knew the limits of the medical system here, so they planned ahead and "sacrificed" tourism and economy earlier than the others, in the end it might prove less damaging to the economy. They started research early so now they can produce their own tests at a very low price to test people massively despite limited financial resources. Local companies started to produce a lot of alcohol too so hydroalcoholic gel is available everywhere at cheap price. Mask is mandatory in public places so it's not that easy to find some, but a lot of garment companies are already producing them in big quantities so they are more and more available.

    With the very hot weather here at the moment I hope it will be enough to contain the virus, we will know in the coming weeks now that the arrival of people from abroad is seriously limited and controlled with quarantine.


  • Hardware Contributor

    In Sweden it seems like Stockholm is preparing now for a big increase in sick people. So far its been very quiet where I live (except on the news of course). Schools still open and most work places open, but people are limiting their social contacts and working from home if possible. Toilet paper out of stock everywhere, but most other products are still there.

    But I live quite rural, so hard to say how its going in the big cities. We dont have any confirmed cases in my town but I guess its just a matter of time.


  • Hardware Contributor

    @sundberg84 said in Coronavirus (way, way, off topic):

    Toilet paper out of stock everywhere

    Great thing in Vietnam about that is most people use a bidet shower aka "bum gun", so toilet paper is not seen as an interesting thing to hoard, and shelves are still full 🙂


  • Hero Member

    Sadly, I'd say the US is full of sitting ducks. I went to the post office yesterday, and I was the only one wearing a P100 respirator or gloves. No one else was wearing a mask or gloves of any kind. People were standing in a fairly long line at the normal separation, not enhanced 6 foot separation. The only precautions I saw anyone take was a woman who managed to open the exit door with her elbow.

    I normally wouldn't even go to the post office, but the place I normally use to accept pre-paid packages for shipment has totally stopped taking them. I presume the reason is to protect their employees from exposure to the public, but this has the consequence of concentrating the public in larger numbers at the post office.

    The supermarkets, which used to be nearly 24/7, have reduced their hours to 8am to 8pm so that their employees have enough time to restock before the customers come flooding back in. Maybe it's also to better protect their restockers from the public as well? While all that may be great for the grocery store, where business is booming, this has had the unintended consequence of making the supermarkets more crowded for customers, which is the opposite of what it should be. And, for whatever reason, the grocery stores seem perpetually packed with people, and even their parking lots are constantly full.

    Clearly the guiding hand of self-interest alone isn't working so well to optimize public health in the large.

    It sounds as though Vietnam is the model we should all be following. As near as I can tell, though, Vietnam's success has had nearly zero press coverage here. That's a tragedy in itself, but not altogether surprising given that the press here has been fairly terrible ever since the collapse of newspapers and magazines.

    @nca78 What do people in Vietnam do for food when they suddenly find themselves under quarantine? I presume they aren't allowed out for it, as it would defeat the purpose of the quarantine. Do they order it delivered, or do they just manage to scrape by on whatever reserves they have on hand?


  • Admin

    @NeverDie
    Here in Sweden many supermarkets open an hour earlier only for the elderly or people with preconditions.


  • Hero Member

    There's some debate about whether a mask is helpful protection or not. I'm not sure what the science indicates. Hackaday has an article on how to DIY one, and it seems to indicate that the coronavirus particle size is actually larger than some bacteria, whereas I had always thought viruses were generally smaller than bacteria. Clearly healthcare workers are wearing them, so that's maybe one sign that they do work. I guess I'm lucky in that I have a P100 dust mask for when I use my circular saw or 3D printing. I'm not sure what might be better than P100. Plainly Home Depot isn't normally stocked for a virus attack. Is there anything commonly off-the-shelf that's better than P100?

    One theory is that even if the virus size is smaller than what a P100 can completely remove, the virus is likely to be lodged inside a globule of spittle or mucus from when someone coughed, rather than floating about in the air in isolation, and so the filter can filter those globules, which are comparatively large, and so thereby block the virus, albeit indirectly.

    I see no downside to it, so if you have one, you might as well wear it when going about in crowded public places. It's still quite easy to breathe with it on. Perhaps it will become the new fashion. 💪



  • @NeverDie It is also said to enter via the eyes, so airtight eye protection is also needed or the mask may well be useless.....at least that is what I have heard....


  • Hero Member

    @skywatch Thanks! It will be hard to find something airtight that fits over my glasses, but I'll look.



  • @skywatch True, but the greatest danger is the airways because you are inhaling.


  • Hero Member

    Just a follow-up: Hackaday's reported size for the virus (https://hackaday.com/2020/03/18/homemade-masks-in-a-time-of-shortage/) is the right order of magnitude but nonetheless a bit off. Hackaday reported 0.1 to 0.2 micron in size, whereas analysis under an electron microscope reports it is 70 to 90nm in size (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045880/). The hellish thing is definitely smaller than even the smallest known bacteria.

    From what I've read so far, there are (obviously) respirator filters that can filter out virus's of even that small particle size, but they are cause for labored breathing and so unpleasant to wear. I guess that's why the ultimate is a powered air purifying respirator (PAPR), which the CDC says offers good protection (https://www.cdc.gov/niosh/npptl/topics/respirators/factsheets/respsars.html) Interestingly, hackaday has a design for one of those too (https://hackaday.com/2007/05/25/diy-powered-respirator/), but who can say how well they work. I may have the parts for one, though, as I was a year or so ago trying to create an air purifier for a 3D printing enclosure. There was a design on thingiverse that I used to house the HEPA filter. It turned out the computer fan I was hoping to use was just nowhere near strong enough to push air through the HEPA filter. Besides, since it wouldn't be formally rated for this use, it would be a total crapshoot as to how well it would actually work.

    Fortunately, the above CDC article says that airborn transmission of small particles is thought to be a relatively rare way to contract COVID-19. It seems that the protective eyewhere is therefore meant to be a guard against being directly sneezed/coughed upon at close proximity.

    So, unless anyone has a better idea for something better than P100, I guess that's about it. I will, though, add over-glasses shop goggles, for whatever good they might do, if anything, since I have them anyway for when working with power tools. Perhaps overspray goggles would be even better? That way it might guard against someone "painting" my eyeballs with their cough. LOL.


  • Hero Member

    Which sources of information about coronavirus have you all found to be the best? I've read CDC, WHO, and FDA, but the best source I've found so far has been Harvard: https://www.health.harvard.edu/diseases-and-conditions/coronavirus-resource-center

    Useful info reported there:

    1. advised to take acetaminophen instead of ibuprofen if you have a fever.
    2. an experiment where a nebulizer was used to send coronavirus into the air shows that infectuous virus laden droplets can remain airborn for up to 3 hours. So, this idea that you see everywhere in the press that the particles can travel only up to 6 feet before they simply drop to the floor just isn't so, and plainly droplets can travel quite some distance in three hours.
    3. Coronavirus tests are prone to false negatives, and it's not even known yet at what stage of the disease a test might indicate positive.
    4. Cancel your kid's play dates.
    5. The incubation period is thought to be anywhere from 3 days to 13 days. The 5 days you commonly read about is just the average (presumably, the median).

    What I like about Harvard is that it's fairly frank about what still isn't known, as compared to, say, the FDA, which makes pronouncements like "there's no evidence that coronavirus can be transmitted by food", which may be literally true, but which probably misleads some people into thinking that such a grand pronouncement is being broadcast because it means food poses zero threat from coronavirus, which isn't what a more careful, literal reading actually implies. It would have been more honest to say that there "isn't yet any evidence." As my high school English teacher was fond of saying, "Absence of evidence isn't evidence of absence." Not surprisingly, fresh produce companies are quick to quote the FDA and reference the FDA as the source. Harvard is more clear that the matter isn't settled, and that the risk may depend a lot on the health of who may have touched the food (and their personal hygiene) before it gets to you. We know that the virus dies in 3 days on plastic or stainless steel, but what about on butter lettuce? That doesn't lend itself well to pealing off of layers, and sanitizing it with common sanitizers... yuck. So, here we won't be buying certain kinds of produce until more is definitely known about this.


  • Hardware Contributor

    @skywatch you're missing the point of the mask. Here it's not worn to protect you, but to protect others if you are infected. So you don't need to have an efficient/medical one, a cloth mask is enough to block saliva spray if you cough or just when you speak. I everyone is wearing a mask, you don't need glasses because no one can project the virus in your face.

    @NeverDie most people starting to put food aside in February here, because with China next door people were afraid it would spread. It's the case for us we had plenty of food in stock and my wife was outside when the quarantine was enabled so she boughts fruits and other fresh food.
    But we can also get deliveries at the entrance of the building and guards will give us so we are not in direct contact with delivery people.


  • Hardware Contributor

    @NeverDie for point 2) it's not comparable to someone coughing, nebulizer makes really tiny droplet that can stay in suspension, when you cough/spit the droplets are much bigger and don't stay airborne for long. But still, I think wearing tissue or even paper masks can limit the spread by blocking the saliva droplets.

    For 3) it happened in Vietnam, a flight attendant was tested negative 4 times before testing positive. Some people have a long incubation period and it seems during part of this incubation period the test fails to detect the virus 😞

    For the FDA unfortunately at some point they have to give recommendations to people, as raw scientific data "It might, it might not" is not enough for people&companies to take a decision. So they have to opt for the most probable situation, and take into account the price and feasibility of things too I guess. If transmission rate is possible but likely extremely low with food, it's not worth spending huge amounts of money to avoid the few cases that it will cause.



  • Here in the Netherlands, schools and daycares are closed for a week now, and stays so at least until the 6th of April. Only people with vital occupations can drop their kids off (hospital personal, and people who work for food companies etc. )

    For the rest, they advise to stay at home and if you need to go out, stay at least 1,5m away from one another. No lockdown yet, they hope these measures will help flatten the curve.

    But people are so very stupid atm. "hey its sunny, let's all go to the park/beach/(fill in crowded place)". I fear that for this reason, they will have a lockdown anytime soon.


  • Hero Member

    Visit to the store.jpg



  • @zboblamont You know the test will only tell you if you have at time of test not if you will not get it in the future so not sure why all of the belief that testing is going to stop you from getting it if you are in contact with people who have it



  • @mntlvr Sorry, obviously I didn't explain that clearly enough.
    There were two strands to testing the Chinese, South Korean etc authorities successfully deployed, and bear in mind these are in communities where voluntary precautions limited the spread, control on movement, distancing, isolation, sterilisation, etc..
    The first strand was a rolling programme of mass checking to identify those with potential symptoms, typically temperature, but there were reports of the Chinese deploying portable scanners to check for lung damage (a much earlier flag) but found no further info on that.
    Only those identified as suspicious went on to specific virus testing, while they traced and checked contacts. Where positive the contacts were advised to be aware and were more rigorously checked.

    Edit - A further complication is that some who recovered fully were infected a second time. This raises questions over immunity, but pretty sure the specialists are trying to figure that out.
    The Vo project/experiment in Italy was an interesting project on global virus testing... As a non-infected city, it's only danger now is inward carriers, but lockdown prevents it...




  • Hero Member

    @zboblamont said in Coronavirus (way, way, off topic):

    Edit - A further complication is that some who recovered fully were infected a second time. This raises questions over immunity, but pretty sure the specialists are trying to figure that out.

    Here's a list of the different theories put forth to explain the double positive test. In classic news style, they're presented with almost equal weight. As a result, the TL;DR is: who knows? 🤷
    https://www.snopes.com/fact-check/covid-19-reinfection/
    My guess: since the stakes are high, you probably want a test that's biased toward false positives over false negatives, and so you would actually expect some double positives from that alone. Whether statistics alone accounts for all of it or not... well, that's what bio statisticians are good for, to tease apart the raw data and figure that out. They should have interviewed one!



  • @NeverDie said in Coronavirus (way, way, off topic):

    They should have interviewed one

    Not sure what US media is like, but in the UK it is expert and eminent virologists such as Pierce Morgan, Nigel Farage and Boris Johnson's father they select to interview.... 👀

    Considering the speed at which this has unfolded the knowledge gleaned has been remarkable, much more to come I suspect.

    UK now has finally gone into lockdown and I believe the US, but there is still considerable disinformation circulating which is not helping, such as Dan Patrick's idiocy on Fox News, reported in the UK along the lines of "WTF... and we thought Boris Hohnson was mad".
    Will leave you with this reality check from Ireland, where numbers are still mercifully low... https://www.independent.ie/irish-news/stay-indoors-im-young-sporty-and-fit-i-never-would-have-thought-id-catch-coronavirus-39070693.html
    Good luck to all, stay safe...


  • Hardware Contributor

    @zboblamont said in Coronavirus (way, way, off topic):

    Not sure what US media is like, but in the UK it is expert and eminent virologists such as Pierce Morgan, Nigel Farage and Boris Johnson's father they select to interview....

    I believe this is some kind of worldwide trend 🤦


  • Hero Member

    @zboblamont According to an op-ed piece in the New York Times, as of yesterday "the United States has tested approximately 313,000 people for the coronavirus, and more than 270,000 have tested negative." i.e. only 13.7% of those who were tested actually tested positive. Given how pre-screened most of those 313,000 had to be in order to even get the test, that 13.7% figure seems a lot lower than I would have expected a priori. Unless the test itself is pretty much garbage, that suggests there must be some other flu with remarkably similar symptoms that's attacking in parallel at the same time. A one-two punch perhaps?


  • Hardware Contributor

    @NeverDie said in Coronavirus (way, way, off topic):

    the United States has tested approximately 313,000 people for the coronavirus

    A lot of tests return negative while people are still in incubation period, but also after symptoms, they seems to be far from 100% reliable. Yesterday they stated that a case currently treated at hospital was tested negative 3 times already, but she is still not considered "cured" in the official statistics.
    My building is still in quarantine, we were supposed to be released from quarantine if all direct contacts tested negative. They tested them all, twice, all negative, but they still maintain the quarantine until the end of the 14 days, and tested all the building yesterday.
    I think it shows how much they trust the tests...

    If you look at the study from Pr Raoult in France who claims chloroquine is an incredible cure, you can see the same patient can be positive one day, negative the next, and positive again on third day. And that's probably the best hospital in France, with the best equipment and very experienced doctors.



  • @NeverDie There do appear to be conflicting reports of test results, but what is not clear in some cases is what the test actually was.
    What IS however very clear is that different strategies of identification, distancing, isolating, quarantine are having various profoundly differing impacts on the spread of the virus, but doing nothing is catastrophic.
    A collaborative article drawing together various aspects of this I'll attach here, a long but illuminating read, and we all have plenty of time of late... The projections for the US were eye-popping, even if the orange faced idiot thinks you'll all be at Easter church services..
    https://medium.com/@tomaspueyo/coronavirus-the-hammer-and-the-dance-be9337092b56


  • Hero Member

    @zboblamont Surely by now everyone realizes that mitigation will help save lives. So, what's holding it back? In the US forward thinkers are starting to question whether a proper prolonged mitigation is even possible without the economic wheels exploding and an altogether different, possibly worse disaster happening, leading to who knows what. It's hard to know what the shape of that might be, but look at how quickly Iraq went barbaric after the US invaded as one possible model of the fallout, and, well, it's not unimaginable. We're all built from the same DNA as those Iraqi's. Mass looting? Definitely, and in poorer cities pretty fast once the groceries run out. And the chaos just gets worse from there. Take existing crime and multiply by 100x. We're just not staffed to control for that. I think we're looking at government rationing and martial law, at a minimum, just to try to keep a lid on things and prevent a boilover.

    So, on the one hand, we think we know the huge cost in lives of not mitigating, but on the other hand, we have little idea of what a prolonged mitigation could lead to, because there's just too many unknowns. Save lives or save society as we know it? And then you look at just whose lives are being saved, and it's mostly a lot of very old people, so you're saving years at end of life rather than saving entire lives. Thus, I can see an argument in favor of letting the chips fall where they may on the virus front but otherwise keeping the world as we know it more or less in tact. Ultimately, I think that's the sort of trade-off that's being debated behind closed doors. If not already, then pretty soon.


  • Hardware Contributor

    @NeverDie depends on who's old. Here in FR, yesterday, 38% of people in reanimation are <60years old. Being in reanimation, means people may also have future health consequences=money cost too.
    Sadly, there are also doctors who died, infected nurses and firemen.. each day seems worse. with confinement, peak is coming very soon here I think.
    Citing a french doctor: "when there is fire, you shouldn't look at the water bill"


  • Hero Member

    @scalz said in Coronavirus (way, way, off topic):

    38% of people in reanimation are <60years old

    They may be in re-animation, but are they dying? So far, US death rate seems governed by age:
    alt text



  • @NeverDie As @scalz aptly quoted, "when there is fire, you shouldn't look at the water bill", unfortunately many of our politicians obsess over little else.
    Frequently ignored on stats relating to age range of fatalities is the realities faced where COVID overwhelms, such as Italy. Those >60 are more likely to have medical complications which increase chances of pneumonia. When numbers attending hospital exceed resources, prioritising WHO gets ventilation kicks in. Over 60s are not priority but are given "assistance" to suffer less, hence inflating fatalities in that age range. A dreadful but necessary choice for doctors typical of a war zone.
    China went on a war footing rapidly, field hospitals, roving screening, contact tracing, they wrote the book. Korea and Singapore refined the techniques successfully, look at their numbers and condition now...

    It is too early to assess the long term damage to health for survivors, but lung damage is fully expected, hence the desperate search for drugs which can have beneficial effect BEFORE infection becomes destructive.

    Finally, the front line as @scalz highlighted. It is crucial medics etc are given all the PPE and kit they need, without it their numbers will deplete, and fatalities will increase... No healthcare system can handle this, again highlighting the importance of strategy deployed by Singapore/Korea etc, screen, test, trace, isolate.

    Watch London in the next 10 days for a textbook example of bean-counter mentality on the health of a populace, it will eclipse Lombardy...


  • Hero Member

    @zboblamont Yes, in an ideal world, I'm all for that. But realistically, for how long can it be maintained? At the moment, we're teetering on recession/depression. As you may have heard, in the US the politicians just recently authorized $2 Trillion direct cash injection to individuals and businesses, and supposedly that means most people will get a roughly $2,000 check. Wonderful. Just how long will that $2,000 last you before it runs out? A week? Two weeks? And then what? Another $2 Trillion? For argument's sake, let's say $4 Trillion/month. Times what? 12 months? 24 months? That would be a range of $48 Trillion to $96 Trillion dollars. Who's going to lend the US that kind of money, especially in an environment where other countries will be needing to borrow similar amounts? Even if everyone got behind that, is it even possible? I just don't see how. In the near term the treasury could print money, but there are limits to even that before dollars lose much of their value to inflation, and if that's the only plan then dollars will become devalued even sooner. US GDP is roughly $20 Trillion. Total existing national debt is $22 Trillion. If there's some way it's possible, I'm just wondering how.

    And I don't mean this to be about the US. The same thing in will probably happen in many if not most other countries.

    My earlier point was simply this: in the US the average life expectancy is 78.6 years. For simplicity, let's set aside the nuances of what that means and take that number at face value. Suppose that by whatever means and at whatever cost you could save a large chunk of the 85+ year olds. Just how much longer do you suppose they would live, even before coronavirus? Maybe a couple more years, on average? And yet, because I doubt the US will triage like the Italians are doing, they'll probably be occupying most of the hospital beds and respirators, because they'll become the sickest in the biggest numbers.



  • Hi guys from Italy. I live in one of the most interested areas by the Virus and I can say that the situation is very bad. I read some of you refer to older people as the main group touched by the virus. That's obviously true but our doctors start to say that the last days people around 50 years old are now increasing in the intensive care units. So, since you all have more time than us, please stay at home and avoid any possible contact with others because this virus is very aggressive. Take care!


  • Hardware Contributor

    @giangired said in Coronavirus (way, way, off topic):

    but our doctors start to say that the last days people around 50 years old are now increasing in the intensive care units

    And yesterday a 16 y.o. girl died in France...

    Edit: no pre-existing condition known and no saturation of hospital/missing equipment involved...
    http://www.leparisien.fr/essonne-91/morsang-sur-orge-91390/julie-16-ans-decedee-du-coronavirus-personne-n-est-invincible-se-desole-sa-soeur-27-03-2020-8288850.php



  • @NeverDie We have been teetering on global recession/depression since 2008 because the underlying problem was never addressed, we just stuck a band-aid on it and carried on with the same "religion". The MMT model is now peeking out amid the UK crisis, and the finance circus are up in arms seeing their QE milk-cow taken away. For the US there are multiple times that resistance and greater lobbying power but that's a whole other issue..

    The problem with your earlier point is what value is placed on a human life, and as both preceding posts made clear the statistical prevalence of older sicker people masks the fact that this virus takes out the young and fit also.
    Without mitigation and ultimately intervention those numbers will escalate dramatically, and you're going to need multiple field hospitals built by the army in record time to cope. It is THAT serious.

    As of this morning the US exceeded China's infections (who tested rigorously and universally v the US scenario) the wider the spread of the virus the greater the number of young and middle-aged who will die, it really is THAT simple.
    As an aside, a 4,000 bed field ICU is almost completed in London just as ALL hospitals are at breaking point, but with it's high population it will still be too little for the tsunami which hits over the next 10 days.
    Time was up 6 weeks ago....


  • Hero Member

    @zboblamont Sounds apocalyptic. Here we've barely left the house since January. Take care, and even more so if you have one or more of the known co-morbidities that puts you at higher risk of death. Plan ahead and identify your source of nearest available supplemental oxygen in case it comes to that.

    The Italians have started to say that hospitals are a major source of caronavirus infection, so I intend to stay away unless it's truly unavoidable.

    In the US there's a push toward hospitals not attempting to resuscitate anyone (aka as "universal DNR") with caronavirus, because healthcare workers don't want to expose themselves to greater risks than they're already taking (which is the stated reason), but probably also legally absolve themselves from taking action when, for example, there simply aren't enough ventilators or other resources to meet demand. Otherwise, they'd be in a constant thrash mode trying to revive someone who has no ventilator access only to be in the same position a moment later, because there's still no spare ventilator to put them on. The only prior precedent for it would be people who officially ask in advance for DNR, with notarized paperwork and instructions to that effect, but this would encompass everyone, even if you've made it clear that's not what you want. I'm guessing it will be approved, but even if it isn't, I can imagine they may adopt that policy unofficially anyway out of either self survival or absurdity avoidance, in which case the public at large may not find out until after the dust has settled, if ever. At least if it were official, people would know what they may be in for if they're unable to breathe on their own, or worse, which is probably the only reason you'd want to be in a hospital in the first place. A brand new catch-22.



  • @NeverDie It's only apocalyptic because politicians made it so or played it down, the nuts claiming it's no worse than flu, or a scam by money manipulators, or Chinese conspiracy, or would damage the economy, only helped obscure the danger to human life by confused messaging.
    Odds of dying in ICU is averaging 17% from the figures I've seen, 27,000 dead so far, no plans to join that number but acutely aware I'm high risk, hence isolated...
    DNR is normal once ICUs are overloaded, a shot of morphine is all they can do to ease the passing.

    For now hunker down and take reasonable precautions, even from our own family members if symptoms show. Until governments are forced to take this seriously and adopt the WHO measures, there is very little upside until you survive it...
    Best of luck over there. 😉


  • Hero Member

    @zboblamont said in Coronavirus (way, way, off topic):

    Odds of dying in ICU is averaging 17%

    If you don't already own one, you may want to buy an oximeter, just to have some objective measure of your condition or a family member's. They're cheap and even now probably pretty widely available. And if you do end up in a hospital, it sounds like you may want to take it there with you. Otherwise, you may be turning blue before anyone notices.


  • Hero Member

    There's growing consensus that the Italian data (not the Chinese data) provides the best model for infection rates and death rates in western countries. Because no one has any natural immunity to this virus, anyone who is exposed will get sick to one degree or another, though some may only be unwitting carriers. That much is a given. Current estimates are that 10% of those exposed will require hospitalization. About half of those "lucky" enough to be on ventilators will die anyway. Cause of death is pneumonia, which in turn is caused a body's excessive inflammatory response. The current average death rate is about 3%. So, when the supply of ventilators and hospital support run out, expect a higher death rate. In the US, the "peak" (i.e. number of new cases per day) is estimated to be sometime in May, with the number of new cases doubling about every 3.5 days up to that peak point. Due to lag, peak death will be sometime in July. It's likely we'll all continue in lockdown until at least August. So, answering my own question from earlier, I'm guessing that yes, the US can self-finance through August. If there is a second wave of infection that comes after, as some predict, then...

    This took some work to dig up and distill, but there it is. Sorry to be the messenger.


  • Admin

    Here in DK, we started with closing down all public schools, and educational institutions 2 weeks ago. For my part, I have been working at my home office for the last 2½ weeks.

    The government is taking a more and more strict approach to the current situation, limiting the freedom of movement, the latest is that (unless you'r a family living together) you are only allowed to be 2 persons in the same area (taking a walk etc.). And the schools etc. are closed at least until 14th of april (after the Easter holidays in denmark)

    Luckily I live in the countryside, so we have lot's of space around us, with forrests etc. So we can get out in the fresh spring air, almost without meeting other people, or if we do meet other people, we can keep a safety distance of 2m. This also means that our local grocery store is not overly crowded with people, when we do shopping, as opposed to the shops in bigger cities.

    As a kind of bonus, I get the opportunity to order some gadgets for my home office, now that I work full time here. "But honey, this thing will unclutter my desktop / make it easier for me to switch between work and hobby".." 😏


  • Hero Member

    If you have a weak temperament or are easily upset, you may want to stop reading now.....

    OK, then, for those who are still reading... I think we all have a shared interest in vetting out what is real vs propaganda. Therefore, how is it that as of this morning the news media is projecting "only" 20,000 dead in the UK and maybe "only" 200,000 dead in the US? Those sound like linear extrapolations to me, not exponential ones. If instead covid-19 really is doubling every 3.5 days, as I've heard from MD's, then in 5 weeks time it's going to be 2^10, i.e. 1000x, worse. Right? So, by that rekoning, in the UK it's going to be a million dead or dying and in the US about 2.5 million. In just 5 weeks from now. Even if social distancing has slowed the rate, the media numbers for the total cost (not just 5 weeks from now) sound way, way off. Or am I missing something? Even if we manage to "flatten the curve," then short of a miracle, that only means it will take longer for the 1000x damage to occur, not that it's going to be avoided. Right? Meanwhile, due to shortages that haven't yet occurred and so aren't yet reflected in the early numbers, I'd wager the outcomes will be even worse than 1000x worse. Does anyone here have a different viewpoint? It seems to me that the official projections are incredibly low-balled, and so they are actually contributing to the problem! The best way to flatten the curve would be for people to have accurate projections, because then they'd be shocked out of their complacency and not be taking unwise risks.

    If you can possibly stay at home and not go out at all for anything for the next two months, I think you'd be wise to do that. Why? Because within that timeframe the actual trendlines should become a lot more apparent to everyone, and so by then people will have dialed in more closely to whatever the actual risks are and adjusted their behavior accordingly. To draw an anology, right now it's like Chernobyl just happened, and yet people are still attending parades outdoors the following day (which is what actually happened) because they were not made aware of the true risks.



  • Screenshot_2020-03-30-19-30-42-952_org.telegram.messenger.jpg


  • Hero Member

    Here the federal government has revised upwards its projections regarding # of infections, # of deaths, and the date of the "peak". They didn't have much choice, given that their prior projections would have soon been invalidated after-the-fact. Their new projections, especially regarding the "peak" date still seems far too conservative. I can only assume they are simply trying to avoid mass panic. Locally the governor has ordered that everyone not involved in giving or receiving essential services stay at home. Finally!

    At least so far no one has talked about whether the food delivery infrastructure will be critically damaged. Because it is a high priority, though, I presume that to one degree or another it will continue to function. Some food items are being rationed, and a few categories, like dried beans, have been wiped out, but overall getting enough food to survive doesn't appear to be a problem if you have the money to pay for it. However, with large segments of the economy effectively "turned off," it seems likely that large numbers of people will be running out of money soon, and with the government here being slow to react...

    Anyone have an updates for their country? I'm interested to hear more about Viet Nam, since it sounded as though it was doing well and there's so little coverage in the press here about it. Unfortunately, the case of China, there's a lot of suspicion that China under-reported how badly they were affected, which would surely have contributed to the under-reaction in the West. The data from Italy seems solid though. It it weren't for the Italians generously sharing their experience, I'm sure things would be even worse throughout the world.

    I'm not sure how much the hospitals can actually do that makes a difference. I had previously read a WHO article that had said that oxygen, which is the first line treatment, didn't actually appear to change the outcomes, though it can keep you alive a bit longer than without it. I'm hearing that 70-80% of those who do advance to ventilation and intubation end up dying even with the added support. I mean, I'm not saying we shouldn't try to do all that we can, just that even our best efforts may only occasionally help--which is suprising. I had thought modern medicine, when properly administered, would make more of a difference.

    🤧


  • Admin


  • Hardware Contributor

    @tbowmo said in Coronavirus (way, way, off topic):

    I don't know if any of you have seen this before:

    https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6

    Yes it's famous, I used to watch it daily when there was mainly a big red dot over China, and a few tiny dots elsewhere. Now they had to reduce the size of dots, and it's red everywhere 😞
    I find the table here https://www.worldometers.info/coronavirus/ easier to see the trends, as the main info to know the progress of the epidemic in a place is the number of new cases / total cases and you can see it right away without clicking on each country.



  • @NeverDie said in Coronavirus (way, way, off topic):

    I'm not sure how much the hospitals can actually do that makes a difference.

    Specialist ICUs can save some of those who are develop viral pneumonia, the reality is that some will die but there is no telling which is which until they succumb. The dilemma is that once ICUs are overloaded the fatality rate climbs due to prioritisation, so the trick is to avoid overwhelming the facilities or accept a higher death rate than may otherwise be the case.

    The easiest way to look at this much is as a flu outbreak, but with the added feature of 10 times the infectivity. For flu there are shots which can provide greater but not complete protection for the more prone, an annual mutation which the manufacturers refine on each cycle.
    In the COVID case there is as yet no vaccine nor natural immunity, but crucially it is infectivity which is the danger as it presents a deluge of critical cases rather than spread over say many months.
    Social distancing and isolation measures can slow the rapid spread, testing vigorously and isolating as in the Singapore and Korean etc models is another successful technique.

    The rest is a political decision...
    This post I thought entirely apt...
    Armageddon.jpg


  • Hero Member

    A quick update regarding how long the virus can live on surfaces. Now it's up to 5 days.

    Here’s how long the virus typically lasts on common surfaces:
    Glass – 5 days.
    Wood – 4 days.
    Plastic & stainless-steel – 3 days.
    Cardboard – 24 hours.
    Copper surfaces – 4 hours.
    https://health.clevelandclinic.org/how-long-will-coronavirus-survive-on-surfaces/

    I'm a bit annoyed by the use of the word "typically." I mean, to be useful, we need to know the high end of the range, not the median.

    If anyone else here has found any other useful tidbits, please post an update.



  • @NeverDie 17 days is the longest I know of SARS-CoV2 surviving in the wild.

    Here is the link to the source....

    https://abcnews.go.com/Health/diamond-princess-traces-coronavirus-17-days-ship-emptied/story?id=69755804


  • Hardware Contributor

    Thank @skywatch that's interesting, especially the nearly 18% of asymptomatic cases, it explains why the epidemic could progress silently in many places before beeing noticed.

    For the "surviving" that's not what I understand, they say "traces of SARS-CoV-2 RNA" it means they can still see it was there on some surfaces, but the virus is probably "dead". Looks more like a trace of blood that you see after a murder.



  • @Nca78 I understood it was viable (i.e. capable of infection) detection, maybe , maybe not. 😉

    But 'the' virus had mutated into at least 33 different versions which might explain why some people/places have more deaths than others. It is also why a cure/vaccine is still a very long way off.


  • Hero Member

    @skywatch said in Coronavirus (way, way, off topic):

    maybe , maybe not

    Yup:

    Does the cruise ship report imply that viruses survive up to 17 days on surfaces?

    Dr Julia Marcus: A CDC investigation of the cruise ship found evidence of viral RNA in cabins that hadn’t yet been cleaned. But to be clear, that just means the virus was detectable – not that it was viable or that contact with those services would have been able to infect someone. (Editor’s note: RNA, or ribonucleic acid, carries the virus’s genetic information.)

    Dr Akiko Iwasaki: It just means that there are parts of the virus that still remain. The virus needs many other components to be intact. If you have bits and pieces of RNA, that’s not going to make a virus, you need an entire intact genome. Just because you had a little piece of RNA doesn’t mean that there’s an infection.
    https://www.theguardian.com/us-news/2020/apr/04/how-long-does-coronavirus-live-on-different-surfaces

    It seems that they only tried to detect either it (possibly intact) or any trace bits of it (possibly not intact), and the way I read it, we don't know whether what they detected was purely unviable bits or whether something still viable was mixed in there as well. I guess if it had turned out that they couldn't even detect it, then that would have been useful information. It's too bad they didn't think ahead enough to test for viability if they did detect something.

    I'm just amazed that by now such basic, practical questions like this, which it should be fairly easy for science to answer, haven't been pinned down with certainty. Or, maybe it has, and we just need to find it somewhere in the scientific literature, unfiltered and undistorted by mass media?


  • Hero Member

    Another interesting tidbit:

    One other surprising finding from the study was that 70 percent of the patients sick enough to be admitted to the hospital did not have a fever. Fever is listed as the top symptom of covid-19 by the CDC, and for weeks, many testing centers for the virus turned away patients if they did not have one. https://www.washingtonpost.com/health/2020/04/22/coronavirus-ventilators-survival/


  • Hero Member

    @skywatch said in Coronavirus (way, way, off topic):

    But 'the' virus had mutated into at least 33 different versions which might explain why some people/places have more deaths than others. It is also why a cure/vaccine is still a very long way off.

    Now that's interesting. I hadn't heard that before. Do you have a source link? Does getting one offer any protection against the others, or will we have to endure 33+ separate assaults? I feel like I've already had it twice this year (all the symptoms except for fever), but I'm unsure as to whether it was just the flu or genuine coronavirus.

    Meanwhile, Oxford University is already doing a double-blind study of an innoculation they've developed. They're testing it on human volunteers (and at least some of the ones receiving the placebo control will need to develop actual covid-19 before they can conclude efficacy). They expect they'll know within 6 months or less whether or not it works.



  • @NeverDie said in Coronavirus (way, way, off topic):

    But 'the' virus had mutated into at least 33 different versions which might explain why some people/places have more deaths than others. It is also why a cure/vaccine is still a very long way off.

    Now that's interesting. I hadn't heard that before. Do you have a source link?

    Of course! 😉

    https://www.scmp.com/news/china/science/article/3080771/coronavirus-mutations-affect-deadliness-strains-chinese-study

    And now we have this...."The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation."

    See the full article here.....

    https://www.scmp.com/news/china/science/article/3080771/coronavirus-mutations-affect-deadliness-strains-chinese-study


  • Hardware Contributor

    @skywatch said in Coronavirus (way, way, off topic):

    See the full article here.....
    https://www.scmp.com/news/china/science/article/3080771/coronavirus-mutations-affect-deadliness-strains-chinese-study

    I would take this with a grain of salt, because of this: "The authors say their findings - based on just 11 patients - are the first to show the mutation could affect the severity of illness."

    You can't pretend to trace mutation and link them to different regions of the world with only 11 patients...

    They claim the strain in Europe is more deadly, but it's the one that arrived in Vietnam (vast majority of the 270 cases recorded here are linked to people arriving from Europe in March) and it doesn't seem to be that deadly: most people are now cured and no none died.


  • Hardware Contributor

    @NeverDie said in Coronavirus (way, way, off topic):

    I'm just amazed that by now such basic, practical questions like this, which it should be fairly easy for science to answer, haven't been pinned down with certainty. Or, maybe it has, and we just need to find it somewhere in the scientific literature, unfiltered and undistorted by mass media?

    The only things they can detect are some specific DNA sequences that are specific to the virus. So the tests can either find those DNA sequences, or not. There are probably ways to check if there are indeed viable viruses in the samples taken, but it must be a very hard task and not worth the energy.
    For survival time of the virus I guess the most practical approach is to put live virus on different surfaces and check after x hours/days if the viruses are still "alive" and able to contaminate people, like the studies you quote earlier. Based on these studies, it doesn't seem credible that the traces found are still dangerous after 17 days.




  • Hero Member

    @skywatch Yipes! Thanks for the heads up.

    The article you linked makes it sound as though it is better at hooking onto and penetrating human cells, but I wonder if anything else of importance may have changed too. For instance, I wonder whether it lives the same length of time on surfaces as the original virus, or whether that information is obsolete wrt the new mutation. That might be an alternate explanation for the higher infection rate.



  • @NeverDie @skywatch Be careful, this has already been outed as fake news...



  • @zboblamont Do you have a link for the 'outing'?


  • Hero Member

    @skywatch said in Coronavirus (way, way, off topic):

    @zboblamont Do you have a link for the 'outing'?

    Maybe this? https://www.nytimes.com/2020/05/06/health/coronavirus-mutation-transmission.html

    It is rather curious that, at least in the US, the Los Angeles Times was the only "major" (usually reputable) newspaper to print the original story.


  • Hero Member

    In the US, the trend is toward removing the lockdown. What do you guys think about that? I mean, if anything, isn't there a more immediate coronavirus threat now than when the lockdown was started? The politicians seem to be saying: "Oh, look, the hospitals didn't get over-run after all." But, in reality, aren't coronavirus infections still growing geometrically? I'm wondering whether the "end the lockown" movement might be the biggest case of GroupThink in world history.



  • @skywatch Sorry, read it in two separate press articles but didn't pay attention which ones... Essentially virologists and epidemiologists reckon this is the most watched and researched bug worldwide, yet ONE lab published a non peer-reviewed paper ?

    @NeverDie There is no one-size-fits-all approach to exit lockdown, the trouble is there are multiple demands to do so none of which are based on science, which is why most of Europe is feeling it's way slowly and with an abundance of caution, the alternative is a lot of dead and overwhelmed health systems.
    Romania has 48/M dead, UK 460, US 236, even if eradicated now there will be 2nd, 3rd etc waves unless you have another strategy to prevent spread. It's all about breaking chains of transmission, and that means dramatically changing "normal" human behaviours.
    Social distancing and sanitation appears to be key, Test/Track/Isolate is also being examined, but no jumping in a plane to Paris for a weekend, it's now 14 days in quarantine.



  • @NeverDie Your name on here is more apt than ever now! 😉

    I think that 'fake news' is a bit harsh. They both agree that mutations have and continue to occur, they do however differ in their opinions on what this actually means.

    @zboblamont I'd rather have another 3 months of lockdown with a clear way out then a rushed one that then comes back after another 30000 Brits die. Lets face it, WE are the test dummies in this scenario and many more will die if the government gets it wrong.



  • @skywatch Agreed, but I'm in a shielded group due to age, and since retired my "normal" ain't everyone else's.

    The immediate problem of lockdown (beyond getting pissed off) is political not health. With so many now on the government payroll (that quaint US term furlough) essentially MMT is in place and working, and it's scaring the sh1t out of those who make a nice living out of MMT denial. If the penny drops as lockdown extends, the big con is over, hence the heavy campaigning to exit lockdown soon, and politicians bricking it. I gather you're a Brit so this may prove interesting if you're not already acquainted with Murphy... https://www.taxresearch.org.uk/Blog/2020/05/05/people-and-jobs-or-wealth-the-government-has-to-decide-which-to-prioritise-and-there-is-only-one-right-answer/
    Our lives will be fundamentally changed for probably 18 months to 2 years with trials and setbacks to keep things under control, what form the steady state takes is currently anybody's guess, but we should know better by 6 months in, around October.



  • @zboblamont I have not read that link entirely, but the title "People and jobs? Or wealth?" made me smile. How will 'wealth' get created without people and jobs?

    Anyway, I will read it all tomorrow when I have more time. Seems that you need some hobbies to avoid getting 'pissed off'. I have been cleaning, gardening, cooking and generally fiddling with mysensors stuff. A few movies as well, it's not as bad as being in an ICU bed I can assure you!

    I think the government should do a half hour presentation to the public about the virus and then 'advise' a lockdown without enforcing it. Then, only the idiots would carry on, as normal, get the disease and die. therefore we could improve the future gene pool by getting rid of some of them. But not everyone would agree with me.

    Also, this is not a war and no infrastructure has been destroyed, to bounce back can happen very quickly when the balance between dead voters/tax payers/GDP contributors (read us, the public) is acceptable for the financial markets to go back to what they were doing before.

    As for now, I understand that alcohol kills the sars-cov-2 virus and so have a lockdown plan to tackle this.......

    20200426_135418.jpg



  • @skywatch I understand your confusion on the wealth/jobs aspect, "the financial markets to go back to what they were doing before " is precisely what we do NOT need if we're not going to avoid boom bust austerity cycles... Mark Blyth does some good lectures on it which may help reset perspectives, his software/hardware computer analogy is particularly helpful.
    Those same vested interests have been provoking public frustration of late in England, but I sincerely hope folks stick with it, idiots are not the only victims if they don't.

    Plenty to keep me occupied here and beer is cheap enough (ca 50p 😉 ), currently fitting IP65 spots in the bathroom, so laying off the beer and looking forward to a shower....



  • The situation is getting worse in my country. Ive read news that around 500 inmates in a single jail was positive of the virus. Im praying we can get through this situation soon.


Log in to reply
 

Suggested Topics

  • 1
  • 3
  • 17
  • 3
  • 956
  • 13
  • 42
  • 10

131
Online

9.4k
Users

10.0k
Topics

104.4k
Posts