With Home Assistant as Operating System it might not work, if the radio is connected to the GPIO of the Pi. The HASS-Os has some restrictions to run software like the Pi gateway beside Homeassistant.
I have currently a setup with a RFM69 connected to the GPIO for the RPI ethernet gateway. Homeassistant runs in a container and the mysensors plugin connects in Homeassistant to localhost or 127.0.0.1. But I have problems with the stability (I think so) with this combination, as seen in this forum.
In my opinion is a Serial (USB-Serial-Converter) Gateway with Homeassistant the best choice. So I want to build another gateway and resinstall my Pi with HASS-Os.