Thanks @Sasquatch. I did some testing also. The values below seem to be the correct ones. I had similar -100 RSSI at all power settings when using the opposite settings. When I use these, I got reasonable RSSI's that changed approximately linearly with the power setting. I got at least 500m range with an E5-LE in a quick test. That's a 5x improvement and there were many obstacles and buildings in the path. I look forward to trying it somewhere where I have more line of sight. I made an update to my code on github.
{STM32WLx::MODE_TX_LP, {HIGH, HIGH}}, // For the E5-LE
{STM32WLx::MODE_TX_HP, {LOW, HIGH}}, // For the regular E5