I have been using Domoticz with MySensors nodes in several different configurations.
The closest I have done to what you are asking is to use the GatewayESP8266MQTTClient version, with one or more sensors connected directly to the ESP8266 running the above client software, so there is no separate Arduino. This is of course wifi only transport from the sensor node via the LAN to Domoticz controller, and it requires a MQTT broker (server).
Similarly I also use Domoticz with ESP8266 running ESPEasy which also transports by wifi, no Arduino. I strongly recommend this combination to get started as the only hardware is a ESP8266 like NodeMCU, Wemos Mini, etc. and your controller host (Linux computer or RPi), and the only software is Domoticz and ESPEasy, both of which require configuration but no customizing code. Of course you can as many sensor nodes as you like.
From reading on this site I got the impression that the ESP8266 is NOT an ideal choice for a general purpose MySensors gateway-to-LAN solution using radio-equipped Arduino sensor nodes, and the W5100 Ethernet Gateway is far better. But I am not using this myself.
Finally I also use MySensors with Arduino and attached radio link to a radio-equipped gateway on a RaspBerry Pi. This is a more complicated solution as you are now dealing with two radios, and both sensor node and gateway software you must configure/customize. It works well, however, and there is the opportunity to wire custom code at the sensor node if you require this.
If you do not have an existing working Domoticz or Mysensors installation, and you simply need data from common sensors, I strongly recommend trying Domoticz + ESPEasy. It is MUCH easier to set up and get running with supported software, as you simply install it on the ESP and configure via a webpage. It is a great help to learn Domoticz without too much complication.
Domoticz is a pretty easy package to get working compared to the others I looked at.